Kenniscentrum Onderwijs en Opvoeding

Decreased Appetite is Associated with Sarcopenia-Related Outcomes in Acute Hospitalized Older Adults


<p>Decreased appetite is one of the main risk factors of malnutrition. Little is known on how appetite changes during hospitalization and after discharge and how it relates with sarcopenia-related outcomes. We analyzed data of the Hospital-ADL study, a multicenter prospective cohort study that followed 400 acutely hospitalized older adults (≥70 year). Appetite (SNAQ), handgrip strength (Jamar), muscle mass (BIA), mobility (DEMMI), and physical performance (SPPB) were assessed within 48 h of admission, at discharge, and at one and three months post-discharge. The course of decreased appetite was analysed by Generalised Estimating Equations. Linear Mixed Model was used to analyse the associations between decreased appetite and the sarcopenia-related outcomes. Decreased appetite was reported by 51% at hospital admission, 34% at discharge, 28% one month post-discharge, and 17% three months post-discharge. Overall, decreased appetite was associated with lower muscle strength (β = -1.089, p = 0.001), lower mobility skills (β = -3.893, p < 0.001), and lower physical performance (β = -0.706, p < 0.001) but not with muscle mass (β = -0.023, p = 0.920). In conclusion, decreased appetite was highly prevalent among acute hospitalized older adults and remained prevalent, although less, after discharge. Decreased appetite was significantly associated with negative sarcopenia-related outcomes, which underlines the need for assessment and monitoring of decreased appetite during and post hospitalization.</p>

Reference van Dronkelaar, C., Tieland, M., Aarden, J. J., Reichardt, L. A., van Seben, R., van der Schaaf, M., van der Esch, M., Engelbert, R. H. H., Twisk, J. W. R., Bosch, J. A., & Buurman, B. M. (2019). Decreased Appetite is Associated with Sarcopenia-Related Outcomes in Acute Hospitalized Older Adults. Nutrients, 11(4), Article 932.
Published by  Urban Vitality 1 January 2019

Publication date

Jan 2019


Carliene van Dronkelaar
Michael Tieland
Lucienne A. Reichardt
Rosanne van Seben
Jos W. R. Twisk
Jos A. Bosch
Bianca M. Buurman


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